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GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

Inhibition of GLI-mediated transcription and tumor cell growth by  small-molecule antagonists | PNAS
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists | PNAS

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth <i>in vitro</
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro

RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via  JNK-dependent but p53-independent mechanism - ScienceDirect
RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism - ScienceDirect

Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression  and Inhibits Proliferation of Canine Osteosarcoma Cells
Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells

Canonical and noncanonical Hedgehog/GLI signaling in hematological  malignancies. | Semantic Scholar
Canonical and noncanonical Hedgehog/GLI signaling in hematological malignancies. | Semantic Scholar

GANT61 | ≥99%(HPLC) | Selleck | Hedgehog/Smoothened inhibitor
GANT61 | ≥99%(HPLC) | Selleck | Hedgehog/Smoothened inhibitor

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013  - International Journal of Cancer - Wiley Online Library
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013 - International Journal of Cancer - Wiley Online Library

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

Reproducibility of academic preclinical translational research: lessons  from the development of Hedgehog pathway inhibitors to treat cancer | Open  Biology
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer | Open Biology

Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... |  Download Scientific Diagram
Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... | Download Scientific Diagram

Schematic overview of different GANT61 target sites. Inhibition of the... |  Download Scientific Diagram
Schematic overview of different GANT61 target sites. Inhibition of the... | Download Scientific Diagram

Frontiers | The Combination of Particle Irradiation With the Hedgehog  Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration  of Cancer Cells Compared to X-Ray Irradiation | Oncology
Frontiers | The Combination of Particle Irradiation With the Hedgehog Inhibitor GANT61 Differently Modulates the Radiosensitivity and Migration of Cancer Cells Compared to X-Ray Irradiation | Oncology

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine  derivatives inhibits melanoma cell growth by inducing replication stress  and mitotic catastrophe | Cell Death & Disease
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe | Cell Death & Disease

The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer? -  Abstract - Europe PMC
The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer? - Abstract - Europe PMC

GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress
GANT 61 (NSC 136476) | Gli1/2 Inhibitor | MedChemExpress

The HH signaling inhibitor GANT61 has an impact on HH target gene... |  Download Scientific Diagram
The HH signaling inhibitor GANT61 has an impact on HH target gene... | Download Scientific Diagram

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

Sonidegib - an overview | ScienceDirect Topics
Sonidegib - an overview | ScienceDirect Topics

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

The role of hedgehog signaling in gastric cancer: molecular mechanisms,  clinical potential, and perspective. - Abstract - Europe PMC
The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective. - Abstract - Europe PMC